Aiming for Medical School?

Recent students from our lab who are now in medical school include:

Bryan Luu [PhD 2018].  Worked on the molecular responses to whole-body dehydration.

-  Luu, B. E., & Storey, K. B. (2018). Solving Donor Organ Shortage with Insights from Freeze Tolerance in Nature: Activating endogenous antioxidant systems with non‐coding RNA to precondition donor organs. BioEssays40(10), 1800092. PMID: 30152131

-  Luu, B. E., Wijenayake, S., Malik, A. I., & Storey, K. B. (2018). The regulation of heat shock proteins in response to dehydration in Xenopus laevisCell Stress and Chaperones23(1), 45-53. PMID: 28676984

-  Luu, B. E., Biggar, K. K., Wu, C. W., & Storey, K. B. (2016). Torpor‐responsive expression of novel microRNA regulating metabolism and other cellular pathways in the thirteen‐lined ground squirrel, Ictidomys tridecemlineatusFEBS letters590(20), 3574-3582. PMID: 27670641

Isabelle MacLean  [BSc - 2017].  Worked on the purification of stress-responsive enzymes.

-  MacLean, I. A., Mattice, A. M., Adam, N. J., & Storey, K. B. (2016). Purification and Characterization of Lactate Dehydrogenase in the Foot Muscle and Hepatopancreas of Otala lacteaThe protein journal35(6), 467-480. PMID: 27858264

- Mattice, A. M., MacLean, I. A., Childers, C. L., & Storey, K. B. (2018). Characterization of pyruvate kinase from the anoxia tolerant turtle, Trachemys scripta elegans: a potential role for enzyme methylation during metabolic rate depression. PeerJ6, e4918. PMID: 29900073

Amanda Mattice  [BSc - 2017].  Worked on the purification of stress-responsive enzymes.

-  MacLean, I. A., Mattice, A. M., Adam, N. J., & Storey, K. B. (2016). Purification and Characterization of Lactate Dehydrogenase in the Foot Muscle and Hepatopancreas of Otala lacteaThe protein journal35(6), 467-480. PMID: 27858264

- Mattice, A. M., MacLean, I. A., Childers, C. L., & Storey, K. B. (2018). Characterization of pyruvate kinase from the anoxia tolerant turtle, Trachemys scripta elegans: a potential role for enzyme methylation during metabolic rate depression. PeerJ6, e4918. PMID: 29900073

Saumya Bansal [BSc - 2015].  Worked on the molecular underpinnings of anoxia tolerance and freeze tolerance.

-  Bansal, S., Biggar, K. K., Krivoruchko, A., & Storey, K. B. (2016). Response of the JAK-STAT signaling pathway to oxygen deprivation in the red eared slider turtle, Trachemys scripta elegans. Gene593(1), 34-40. PMID: 27502419

- Bansal, S., Luu, B. E., & Storey, K. B. (2016). MicroRNA regulation in heart and skeletal muscle over the freeze–thaw cycle in the freeze tolerant wood frog. Journal of Comparative Physiology B186(2), 229-241. PMID: 26660652

Ashley Gerber  [BSc - 2016].  Worked on the stress-responsive role of microRNAs in the brains of hibernating squirrels.

Victoria Gerber  [BSc - 2015].  Worked on anti-apoptotic responses during freezing and anoxia in wood frogs.

- Gerber, V.E.M, Wijenayake, S., and Storey, K.B. (2016) Anti-apoptotic response during anoxia and recovery in a freeze-tolerant wood frog (Rana sylvatica). PeerJ 4:e1834. PMID: 27042393

Johnny Abboud  [MSc - 2015].  Worked on the regulation of pyruvate kinase and glycerol-3-phosphate dehydrogenase and their role in polyol cryoprotectant production in freeze tolerant insects.

- Abboud, J. and Storey, K.B. 2013. Novel control of lactate dehydrogenase from the freeze tolerant wood frog: role of posttranslational modifications. Peer J. 1:e12, . PMID: 23638346

Andrew Rouble  [MSc - 2014].  Worked on the reversible protein acetylation in the regulation of mammalian hibernation.

- Rouble, A.N. and Storey, K.B. 2015. Characterization of the SIRT family of NAD+-dependent protein deacetylases in the context of a mammalian model of hibernation, the thirteen-lined ground squirrel. Cryobiology. PMID: 26277038

- Rouble, A.N., Tessier, S.N., and Storey, K.B. 2014. Characterization of adipocyte stress response pathways during hibernation in thirteen-lined ground squirrels. Mol. Cell. Biochem. 393, 271-282. PMID 24777704

- Rouble, A.N., Biggar, K.K. and Storey, K.B. 2014. A high-throughput protocol for message RNA quantification using RNA dot-blots. Anal. Biochem. 452, 31-33. PMID 24560727

- Rouble, A.N., Hefler, J., Mamady, H., Storey, K.B. and Tessier, S.N. 2013. Anti-apoptotic signaling as a cytoprotective mechanism in mammalian hibernation. Peer J. 1:e29. PMID: 23638364

Joshua Hefler  [BSc - 2012].  Worked on cytoprotective signalling pathways in hibernating squirrels.

- Hefler, J., Wu, C.-W. and Storey, K.B. 2015. Transcriptional activation of p53 during cold induced torpor of the 13-lined ground squirrel Ictidomys tridecemlineatus. Biochem. Res. Intl. 2015, Article ID 731595, 11 pp. PMID: 26843984.

- Rouble, A.N., Hefler, J., Mamady, H., Storey, K.B. and Tessier, S.N. 2013. Anti-apoptotic signaling as a cytoprotective mechanism in mammalian hibernation. Peer J. 1:e29. PMID: 23638364

Helen Alex Holden [MSc - 2011].  Worked on immune responses and the SMAD family in the wood frog and the African clawed frog during environmental stress.

- Holden, H.A. and Storey, K.B. 2011. Reversible phosphorylation regulation of NADPH-linked polyol dehydrogenase in the freeze-avoiding gall moth, Epiblema scudderiana: Role in glycerol metabolism. Arch. Insect Biochem. Physiol. 77, 32-44. PMID: 21400585.

- Katzenback, B.A., Holden, H.A., Falardeau, J., Childers, C., Hadj-Moussa, H., Avis, T.J. and Storey, K.B. Regulation of the Rana sylvaticabrevinin-1SY antimicrobial peptide during development and in dorsal and ventral skin in response to freezing, anoxia, and dehydration. J. Exp. Biol. 217:1392-1401. PMID: 24436376

Marcus Allan  [MSc - 2010].  Worked on the nuclear factor (NF)-kappaB regulation in the hibernating thirteen-lined ground squirrel.

- Allan, M. and Storey, K.B. 2012. Expression of NF-κB and downstream antioxidant genes in skeletal muscle of hibernating ground squirrels, Spermophilus tridecemlineatus. Cell Biochem. Funct. 30,166-174. PMID: 22086848

- Ramnanan, C.J., Allan, M.E., Groom, A.G. and Storey, K.B. 2009. Regulation of global protein translation and protein degradation in aerobic dormancy. Mol. Cell. Biochem. 323, 9-20. PMID: 19011953

Tarek Abd El Halim [BSc - 2007].  Worked on ....

Amy Groom [BSc - 2006].  Worked on ...

- Biggar, K.K., Groom, A.G. and Storey, K.B. 2011. Hypometabolism and turtles: Physiological and molecular strategies of anoxic survival. In:Hypometabolism: Strategies of Survival in Vertebrates and Invertebrates. (Nowakowska, A. and Caputa, M., ed.), Research Signpost, Kerala, India, pp. 57-94. Book Chapter.

- Ramnanan, C.J., McMullen, D.C., Groom, A.G. and Storey, K.B. 2010. The regulation of AMPK signaling in a natural state of profound metabolic rate depression. Mol. Cell. Biochem. 335, 91–105. PMID: 19756961

- Ramnanan, C.J., Allan, M.E., Groom, A.G. and Storey, K.B. 2009. Regulation of global protein translation and protein degradation in aerobic dormancy. Mol. Cell. Biochem. 323, 9-20. PMID: 19011953

- Ramnanan, C.J., Groom, A.G. and Storey, K.B. 2007. Akt and its downstream targets play key roles in mediating dormancy in land snails. Comp. Biochem. Physiol. B 148, 245-255. PMID: 17611133