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Research Interests

The Storey Lab studies the biochemical adaptations and molecular mechanisms that allow animals to adapt to and endure extreme environmental stresses such as the deep cold, oxygen deprivation, and desiccation.

Positions Available

New projects are available for Graduate students and Honours students. For a more detailed description of the projects currently available for Graduate and Honours students visit the Opportunities page. 

Contact Information

Email: Kenneth_Storey@carleton.ca
Email: Jan_Storey@carleton.ca

Telephone: +1 (613) 520-2600 x3678
Fax: +1 (613) 520-3749

Featured New Publications 

Storey, K.B. and Storey, J.M. 2017. Molecular physiology of freeze tolerance in vertebrates. Physiol. Rev. 97, 623–665. PMID: 28179395

Biggar, K.K. and Storey, K.B. 2017. Exploration of low temperature microRNA function in an anoxia tolerant vertebrate ectotherm, the red-eared slider turtle (Trachemys scripta elegans). J. Thermal Biol.  68, 139-146.  PMID: 28689715

Wu, C.-W., Tessier, S.N. and Storey, K.B. 2017. Regulation of the insulin-Akt signaling pathway and glycolysis during dehydration stress in the African clawed frog Xenopus laevis. Biochem. Cell Biol. 95: 663–671. PMID: 28708941

Zhang, J. and Storey, K.B. 2017. Insect cold hardiness: the role of mitogen-activated protein kinase and Akt signaling in freeze avoiding larvae of the goldenrod gall moth, Epiblema scudderiana. Insect Mol. Biol. 26(2), 181-189. PMID: 27880024

Tessier, S.N., Luu, B.E., Smith, J.C. and Storey, K.B. 2017.  The role of global histone post-translational modifications during mammalian hibernation. Cryobiology 75, 28-36. PMID: 28257856

Zhang, Y., Al-attar, R. and Storey, K.B. 2017. TonEBP/NFAT5 regulates downstream osmoregulatory proteins during freeze-thaw stress in the wood frog. Cryobiology 79, 43-49.  PMID: 28947252

Green, S.R. and Storey, K.B. 2017. Regulation of glutamate dehydrogenase (GDH) in response to whole body freezing in wood frog liver linked to differential acetylation and ADP-ribosylation. Arch. Biochem. Biophys. 636, 90–99. PMID: 29056417

Herinckx, G., Hussain, N., Opperdoes, F.R., Storey, K.B., Rider, M.H. and ­Vertommen, D. 2017.  Changes in the phosphoproteome of brown adipose tissue during hibernation in the ground squirrel, Ictidomys tridecemlineatus. Physiol. Genom. 49 (9), 462-472. PMID: 28698229

Adamson, K.J., Wang T., Rotgans, B., Kruangkum, T., Kuballa, A.V., Storey, K.B. and Cummins, S.F. 2017. Genes and associated neuropeptides involved with aestivation in a land snail. Gen. Comp. Endocrinol. 246, 88-98. PMID: 26497253

Hawkins, L.J. and Storey, K.B. 2017. Improved high-throughput quantification of luminescent microplate assays using a common Western-blot imaging system. MethodsX 4, 413-422.

 

Special LEMUR Series:  Torpor in a Primate

The gray mouse lemur: a model for studies of primate metabolic rate depression. Storey, K.B. 2015. Genom. Proteom. Bioinform. 13, 77–80. PMID: 26102318

Primate torpor: Regulation of stress-activated protein kinases during daily torpor in the gray mouse lemur, Microcebus murinus. Biggar, K.K., Wu, C.-W., Tessier, S.N., Zhang, J., Pifferi, F., Perret, M. and Storey. K.B. 2015. Genom. Proteom. Bioinform. 13, 81–90. PMID: 26093282

Regulation of the PI3K/AKT pathway and fuel utilization during primate torpor in the gray mouse lemur, Microcebus murinus. Tessier, S.N., Zhang, J., Biggar, K.K., Wu, C.-W., Pifferi, F., Perret, M. and Storey, K.B. 2015. Genom. Proteom. Bioinform. 13, 91–102.   PMID: 26092184

Regulation of torpor in the gray mouse lemur: transcriptional and translational controls and role of AMPK signaling. Zhang, J., Tessier, S.N., Biggar, K.K., Wu, C.-W., Pifferi, F., Perret, M. and Storey, K.B. 2015. Genom. Proteom. Bioinform. 13, 103–110.  PMID: 26092186

Modulation of gene expression in key survival pathways during torpor in the gray mouse lemur, Microcebus murinus. Biggar. K.K., Wu, C.-W., Tessier, S.N., Zhang, J., Pifferi, F., Perret, M. and Storey, K.B. 2015. Genom. Proteom. Bioinform. 13, 111–118. PMID: 26093281

Induction of antioxidant and heat shock protein responses during torpor in the mouse lemur, Microcebus murinus. Wu, C.-W., Biggar, K.K., Tessier, S.N., Zhang, J., Pifferi, F., Perret, M. and Storey, K.B. 2015. Genom. Proteom. Bioinform. 13, 119–126.  PMID: 26092183

Cytokine and antioxidant regulation in the intestine of the gray mouse lemur (Microcebus murinus) during torpor. Tessier, S.N., Katzenback, B.A., Pifferi, F., Perret, M. and Storey, K.B. 2015. Genom. Proteom. Bioinform. 13, 127–135. PMID: 26092185