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Research Interests

The Storey Lab studies the biochemical adaptations and molecular mechanisms that allow animals to adapt to extreme environmental stresses such as the deep cold, oxygen deprivation, and desiccation.

Positions Available

New projects are available for Graduate students and Honours students. For a more detailed description of the projects currently available for Graduate and Honours students visit the Opportunities page. 

Contact Information

Email: Kenneth_Storey@carleton.ca
Email: Jan_Storey@carleton.ca

Telephone: +1 (613) 520-2600 x3678
Fax: +1 (613) 520-3749

Featured New Publications 

Biggar KK, and Storey KB. 2018. Functional impact of microRNA regulation in models of extreme stress adaptation. J. Mol. Cell Biol. 10(2), 93-101. PMID: 29206937

Biggar KK, Luu BE, Wu C-W, Pifferi F, Perret M, and Storey KB. 2018. Identification of novel and conserved microRNA and their expression in the gray mouse lemur, Microcebus murinus, a primate capable of daily torpor. Gene 677, 332-339. PMID: 30103007

Chanon S, Chazarin B, Toubhans B, Durand C, Chery I, Robert M, Vieille-Marchiset A, Swenson JE, Zedrosser A, Evans AL. Brunberg S, Arnemo JM, Gauquelin-Koch G, Storey KB, Simon C, Blanc S, Bertile F, Lefai E. 2018. Proteolysis inhibition by hibernating bear serum leads to increased protein content in human muscle cells. Scientific Reports 8(1), 5525. PMID: 29615761

Hadj‐Moussa H, and Storey KB. 2018. Bringing nature back: using hibernation to reboot organ preservation. The FEBS journalPMID: 30347515 

Hadj‐Moussa H, Green SR, and Storey KB. 2018. The Living Dead: Mitochondria and Metabolic Arrest. IUBMB life.  70 (12), 1260–1266. PMID: 30230676

Hawkins LJ, Al-attar R, and Storey KB. 2018. Transcriptional regulation of metabolism in disease: from transcription factors to epigenetics. PeerJ 6, e5062. PMID: 29922517

Logan SM, Watts AJ, and Storey KB. 2018. Brain Dead: The Dynamic Neuroendocrinological Adaptations During Hypometabolism in Mammalian Hibernators. Model Animals in Neuroendocrinology: From Worm to Mouse to Man, 207-231. Chapter link

Luu BE, and Storey KB. 2018. Solving Donor Organ Shortage with Insights from Freeze Tolerance in Nature: Activating endogenous antioxidant systems with non‐coding RNA to precondition donor organs. BioEssays40(10), 1800092. PMID: 30152131

Storey KB, and Storey JM. 2017. Molecular physiology of freeze tolerance in vertebrates. Physiological Reviews97(2), 623-665. PMID: 28179395

Wijenayake S, Hawkins LJ, and Storey KB. 2018. Dynamic regulation of six histone H3 lysine (K) methyltransferases in response to prolonged anoxia exposure in a freshwater turtle. Gene 639, 50-57. PMID: 29382574

In the News!

               

Special MONITO DEL MONTE Series:  Torpor in a South American Marsupial

Strategies of biochemical adaptation for hibernation in a South American marsupial 1. Mitogen-activated protein kinases and the cell stress response. Wijenayake S, Luu BE, Zhang J, Tessier SN, Quintero-Galvis JF, Gaitán-Espitia JD, Nespolo RF, and Storey KB. 2018. Comp. Biochem. Physiol. B 224, 12-18. PMID: 29247845

Strategies of biochemical adaptation for hibernation in a South American marsupial, Dromiciops gliroides: 2. Control of the Akt pathway and protein translation machinery. Luu BE, Wijenayake S, Zhang J, Tessier SN, Quintero-Galvis JF, Gaitán-Espitia JD, Nespolo RF. and Storey KB. 2018. Comp. Biochem. Physiol. B 224, 19-25. PMID: 29247846

Strategies of biochemical adaptation for hibernation in a South American marsupial, Dromiciops gliroides: 3. Activation of pro-survival response pathways. Luu BE, Wijenayake S, Zhang J, Tessier SN, Quintero-Galvis, JF, Gaitán-Espitia JD, Nespolo RF, and Storey, KB. 2018.  Comp. Biochem. Physiol. B 224, 26-31. PMID: 29248591

Strategies of biochemical adaptation for hibernation in a South American marsupial, Dromiciops gliroides: 4. Regulation of pyruvate dehydrogenase complex and metabolic fuel selection. Wijenayake S, Luu BE, Zhang J, Tessier SN, Quintero-Galvis JF, Gaitán-Espitia JD, Nespolo RF, and Storey KB. 2018. Comp. Biochem. Physiol. B 224, 32-37. PMID: 29247844. PMID: 29247844

The hibernating South American marsupial, Dromiciops gliroides, displays torpor-sensitive microRNA expression patterns. Hadj-Moussa H, Moggridge JA, Luu BE, Quintero-Galvis JF, Gaitán-Espitia JD, Nespolo RF, and Storey KB. 2016. Sci. Rep. 6, 24627. PMID: PMID: 27090740